Informace o projektu
Drug design is not about a fashionable drug box (ddnafdb)

The aim of the course is to introduce the general university public to the view of the drug as its own effective molecule and to acquaint students with the path that leads to the discovery of the drug and its introduction into medical practice. From the perspective of historical development, current state and future perspectives, the course describes the sources of biologically active molecules and how these original "lead compounds" can be improved and optimized so that they can serve as effective and safe drugs for the present and future. It also focuses on the difference between "small molecules", ie classic "chemical" drugs, and "large" molecules, so-called bio-drugs, whose importance in the treatment of serious diseases has increased significantly in recent decades. The course also describes the role of chemical, biological, mathematical, physical, computer and other disciplines in drug development, mentions, among other things, the use of computer modeling of potentially effective molecules and their interactions with the target structure, such as receptor or enzyme active site in virtual space.