PharmDr. Tomáš Goněc, Ph.D.

2020

• Hydroxynaphthalenecarboxamides and substituted piperazinylpropandiols, two new series of BRAF inhibitors. A theoretical and experimental study

  CAMPOS L.E. GARIBOTTO F. ANGELINA E. KOS J. GONĚC Tomáš MARVANOVÁ Pavlína VETTORAZZI M. ORAVEC M. JENDRZEJEWSKA I. JAMPILEK J. ALVAREZ S.E. ENRIZ R.D.

  Article in Periodical

  Bioorganic Chemistry, year: 2020, volume: 103, edition: 104145, DOI

• Indol-2-Carboxylic Acid Esters Containing N-Phenylpiperazine Moiety - Preparation and Cholinesterase-inhibiting Activity

  PADRTOVÁ Tereza MARVANOVÁ Pavlína KUBÍNOVÁ Renata CSÖLLEI Jozef FARSA Oldřich GONĚC Tomáš ODEHNALOVÁ Klára OPATŘILOVÁ Radka PAZOUREK Jiří SYCHROVÁ Alice ŠMEJKAL Karel MOKRÝ Petr

  Article in Periodical

  Current organic synthesis, year: 2020, volume: 17, edition: 7, DOI

• Ring-Substituted 1-Hydroxynaphthalene-2-Carboxanilides Inhibit Proliferation and Trigger Mitochondria-Mediated Apoptosis

  KAUEROVÁ Tereza GONĚC Tomáš JAMPÍLEK Josef HAFNER Susanne GAISER Ann-Kathrin SYROVETS Tatiana FEDR Radek SOUČEK Karel KOLLÁR Peter

  Article in Periodical

  International Journal of Molecular Sciences, year: 2020, volume: 21, edition: 10, DOI

2019

• Bioactivity of Methoxylated and Methylated 1-Hydroxynaphthalene-2-Carboxanilides: Comparative Molecular Surface Analysis

  MICHNOVÁ Hana POSPÍŠILOVÁ Šárka GONĚC Tomáš KAPUSTÍKOVA Iva KOLLÁR Peter KOZIK Violetta MUSIOL Robert JENDRZEJEWSKA Izabela VANČO Ján TRÁVNÍČEK Zdeněk ČÍŽEK Alois BAK Andrzej

  Article in Periodical

  Molecules, year: 2019, volume: 24, edition: 16, DOI

• Cathodic Voltammetric Determination of a Nitro Substituted 1-Hydroxynaphthalene-2-carboxanilide in Dimethyl Sulfoxide in Electrochemical Microcell

  GAJDAR J GONĚC Tomáš JAMPILEK J BRÁZDOVÁ Marie BÁBKOVÁ Z FOJTA Miroslav BAREK Jiří FISCHER J

  Article in Proceedings

  PROCEEDINGS OF INTERNATIONAL CONFERENCE MODERN ELECTROCHEMICAL METHODS XXXIX, year: 2019

• Design and synthesis of anticancer 1-hydroxynaphthalene-2-carboxanilides with a p53 independent mechanism of action

  SPACZYNSKA E MROZEK-WILCZKIEWICZ A MALARZ K KOS J GONĚC Tomáš ORAVEC M GAWECKI R BAK A DOHANOSOVA J KAPUSTIKOVA I LIPTAJ T JAMPILEK J MUSIOL R

  Article in Periodical

  Nature Scientific Reports, year: 2019, volume: 9, DOI

• Preparation and Hydro-Lipophilic Properties of Methoxylated and Methylated 1-Hydroxynaphthalene-2-Carboxanilides.

  KAPUSTIKOVA I GONĚC Tomáš KOS J SPACZYNSKA E ORAVEC M DOHANOSOVA J LIPTAJ T MUSIOL R JAMPILEK J

  Article in Proceedings

  Proceedings, year: 2019

• Searching new structural scaffolds for BRAF inhibitors. An integrative study using theoretical and experimental techniques

  CAMPOS LE GARIBOTTO FM ANGELINA E KOS J TOMASIC T ZIDER N KIKELJ D GONĚC Tomáš MARVANOVÁ Pavlína MOKRÝ Petr JAMPILEK J ALVAREZ SE ENRIZ RD

  Article in Periodical

  Bioorganic Chemistry, year: 2019, volume: 91, DOI

2018

• Investigation of Hydro-Lipophilic Properties of N-Alkoxyphenylhydroxynaphthalenecarboxamides

  KAPUSTIKOVA I BAK A GONĚC Tomáš KOS J KOZIK V JAMPILEK J

  Article in Periodical

  Molecules, year: 2018, volume: 23, edition: 7, DOI

• Voltammetry of a Novel Antimycobacterial Agent 1-Hydroxy-N-(4-nitrophenyl)naphthalene-2-carboxamide in a Single Drop of a Solution

  GAJDAR J GONĚC Tomáš JAMPILEK J BRÁZDOVÁ Marie BABKOVA Z FOJTA Miroslav BAREK J FISCHER J

  Article in Periodical

  Electroanalysis, year: 2018, volume: 30, edition: 1, DOI